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EU-RL PROGRAM OF THE YEAR 2018

Published on 11/01/2018

  ANALYTICAL DEVELOPMENTS:        EU-NRLs / EU-RL Collaborative Study on the analytical strategies for multi-antimicrobial control using LC-HRMS instruments (final)      New confirmatory LC-MS/MS method for beta-lactam residues in meat and milk      Enhancing the control for multi-dye residues in aquaculture products by targeted method with LC-MS/MS and by untargeted approach using LC-HRMS      Extending LC-HRMS screening analysis to all group B1 antimicrobial residues in different species/products      Validation of new confirmatory LC-MS/MS monitoring of nitrofuran residues in tissues and including the nifursol metabolite     Confirmatory LC-MS/MS monitoring of colistin residues       Evaluation of  innovative technologies for rapid screening of veternary antimicrobial residues in Foodstuffs - Electrochemical biosensors      Evaluation of 4 ELISA kits for the screening of nitrofuran metabolites (AOZ, AMOZ, SEM and AHD) in aquaculture products   ANNUAL WORKSHOP            Control of antimicrobial and dye residues in food from animal origin - (Week 26: 28-29 June)   PROFICIENCY TESTS:        Screening and Confirmation of Banned Antimicrobial Substances in Porcine Meat and Urine  (March-June 2018)      Screening and Confirmation of Authorized Antimicrobial Residues in Milk   (September-November 2018)

List of analytical instruments available at Anses-Fougères

Published on 28/12/2016

Immunology-Biosensors : Biosensor : Biacore X from Biacore Co. Biosensor : Evidence from Randox Co. ELISA instruments : Microplate Reader type Spectra Count from Packard Bioscience Co. Microplate Washer LP40 type WinWasher from Packard Bioscience Co. Physico-chemistry instruments :  HPLC-DAD : Agilent 1100 Series HPLC-DAD : Agilent 1260 Infinity II Series HPLC-DAD-Fluo : ThermoFinnigan TSP P1000XR equipped with AS3000 Autosampler and Spectra Focus multi-Lambda UV6000LP detector and Jasco FP-1520 Spectrofluorimeter LC-MS/MS : Waters Alliance LC system equipped with Triple Quad Quattro LCZ Micromass mass spectrometer LC-MS/MS : HP1100 LC system equipped with Triple Quad API4000 AB-Sciex mass spectrometer LC-MS/MS : Surveyor LC system equipped with Triple Quad TSQ Quantum Thermo-Finnigan mass spectrometer LC-MS/MS : Accela LC system equipped with Triple Quad Vantage Thermo-Finnigan mass spectrometer (1) LC-MS/MS : Accela LC system equipped with Triple Quad Vantage Thermo-Finnigan mass spectrometer (2) LC-MS/MS : Shimadzu LC system equipped with Q-TRAP API 5500 AB-Sciex mass spectrometer LC-HRMS : Accela Thermo Finnigan LC system equipped with a Linear Trap and Orbital Trap Thermo-Finnigan mass spectrometer LC-HRMS : U-HPLC Vanquish ThermoFisher LC system equipped with a Q-Exactive Plus HCD Orbital Trap ThermoFisher mass spectrometer   Back to Home  

Proficiency tests

Published on 07/01/2016

The EU-RL Anses-Fougeres provides Proficiency Testing (PT) for NRLs in charge of control for antibiotic and dye residues in food from animal origin. For banned antibiotic substances in all foodstuff products (A6 group : chloramphenicol and nitrofurans ;  B2f group : carbadox and olaquindox) For non authorised substances (B3e group : dyes in aquaculture products) For authorised antibiotics (B1 group) regulated with MRL in all foodstuff products PT Program of the year  2018 PT for the screening and confirmation of chloramphenicol residues in pig urine and muscle (first semester) PT for the screening and confirmation of multiantibiotic residues in milk (second semester) PT Program of the year 2017 1. PT for the screening and confirmation of antibiotic residues in aquaculture products :        February-April  2. PT for screening and confirmation of banned substances (chloramphenicol and nitrofuranes) in pig muscle     Previous PT of past years PT Code Year Matrix Species Molecules 16-MM 2017 Fish Trout fish Several B1 antibiotics 16-LD 2016 Flesh Shrimps Nitrofuranes,CAP and Dyes 16-KO 2016 Honey Bee Several B1 antibiotics 15-JJ 2015 Muscle Pig Nitrofuranes 15-JS 2015 Muscle Pig Several B1 antibiotics 14-HM 2014 Muscle,urine Pig Chloramphenicol 14-IT 2014 Milk Cow, Goat Several B1 antibiotics 13-FT 2013 Muscle Pig Carbadox Olaquindox 13-GP 2013 Flesh Shrimp Dyes 11-DA 2011 Honey Bee Nitrofuranes 11-DM 2011 Fish Trout fish Quinolones 10-BI 2010 Fish Trout fish Chloramphenicol 10-BQ 2010 Muscle Pig Several B1 antibiotics 09-AE 2009 Fish Trout fish Dyes 09-ZU 2009 Milk Cow Several B1 antibiotics YE 2008 Muscle Pig Nitrofuranes YK 2008 Meat juice Multi-species Betalactames, sulfamides,  macrolides, tetracyclines YS 2008 Muscle Pig Tetracycline XI 2007 Honey Milk   Chloramphenicol XV 2007 Milk Cow Betalactames WF 2006 Muscle Pig Carbadox Olaquindox WW 2006 Eggs Hen sulfamides VL 2005 Honey Bee  Sulfamides, Tetracyclines          VS 2005 Muscle Pig OTC, Dano, Tylosine ,S-dimethoxine          UU 2004 Muscle Pig Chloramphenicol VC 2004 Muscle Pig Nitrofuranes VF 2004 Fish Trout Malachite green TW 2003 Milk   Aminoglycosides UG 2003 Muscle Pig Macrolides UQ 2003 Milk Cow  OTC,TC, PG,Cloxacilline , Neo, Tylo,S-methazine SN 2002 Milk Cow Sulfamides TC 2002 Muscle Pig Chloramphenicol TI 2002 Muscle Pig Sulfamides TQ 2002 Flesh Shrimp Nitrofuranes SJ 2001 Muscle   Chloramphenicol SL 2001 Muscle   Quinolones SQ 2001 Muscle   Penicillines SS 2001...

Symposia Contributions

Published on 09/12/2015

Last updated 2018.05.07   Contribution of Anses-Fugeres to the 8th International Symposium on Recent Advances in Food Analysis, November 7-10, 2017, Prague, Czech Republic Confirmation by LC-MS/MS of Macrolide, Lincosamide, Penicillin, and Cephalosporin Residues in Muscle from Animal Intended for Human Consumption,  Gaugain M., Guichard P., Fourmond MP., Verdon E.? Hurtaud-Pessel D. Development of a screening method for multiclass veterinary drug residues using High Resolution Mass Spectrometry, Hurtaud-Pessel D., Couedor P., Verdon E. Dye Residues in Aquaculture Products: targeted and metabolomics mass spectrometric approaches to track their abuse, Dubreil E., Mompelat S., Guitton Y., Danion M., Morin T., Hurtaud-Pessel D., Verdon E. Contribution of Anses-Fougeres to the 10th Scientific Days of RFMF (French Network for Metabolomic and Fluxomic), May 31 - June 2, 2016, Montpellier, France Recherche par LC-HRMS de biomarqueur(s) d'exposition des volailles à un antibiotique appartenant à la famille des céphalosporines: le ceftiofur, Mompelat S., Abjean JP., Hurtaud-Pessel D., Verdon E. Contribution of Anses-Fougeres to Metabolomics 2016, 12th Annual Conference of the Metabolomic Society, June 27-30, 2016, Dublin, Ireland Assessment of metabolomics approach for the screening of illegal administration of cephalosporins in laying hens, Gaugain M., Foumond MP., Manceau J., Rolland JG., Verdon E., Hurtaud-Pessel D. Contributions of Anses-Fougeres to EURORESIDUE VIII, Symposium on Residues of Veterinary Drugs in Food, 23-25 May 2016, Eegmond an Zee, The Netherlands Dye residues in aquaculture products: Implementationof targeted and non-targeted approaches, Dubreil E., Kromer V., Mompelat S., Guitton Y., Royer AL., Danion M., Morin T., Verdon E. Determination of ampicillin residues below its EU regulatory limits in muscle, liver, and plasma of chicken by LC-MS/MS, Mompelat S., Couedor P., Dubreil E., Travel A., Engel E., Hurtaud-Pessel D., Verdon E. Optimization of an extrcation method in attempt to develop a multi-class antibiotic residues in Honey using LC-MS/MS, El Hawari K., Mokh S., Doumyati S., Al Iskandarani M., Verdon E. Results of Proficiency Testing for the Analysis of (Fluoro)Quinolone Residues in Trout (Oncorhynchus Mykiss Species), Fuselier R., Verdon E. Contribution of Anses-Fougeres to RAFA2015, the 7th International Symposium of Recent Advances in Food Analysis, November 3-6, 2015, Prague, Czech Republic A French Study on Conventional and Organic Meat: Investigation for Veterinary Drug Residues, Dubreil E., Mompelat S., Fourmond MP., Travel A., Dervilly-Pinel G., Engel E., Hurtaud-Pessel D., Verdon E. Which marker residues for carbadox control in pig tissues? - Validation of a LC-MS/MS method for the determination of metabolites of carbadox in muscle and in liver. Hurtaud-Pessel D., Couedor P., Laurentie M., Verdon E. Contribution of Anses-Fougeres to Conference EFSA-Expo2015 "Shaping the Future of Food Safety, Together", October 14-16, 2015, Milan, Italy From 1993 to 2015 : more than 20 years of a EU-Reference Laboratory activity for networking key EU-MS National Reference Laboratories for the food safety control in the European Union - Shaping the future of control and expertise of VMP residues in food. Verdon E., Sanders P. Contribution of Anses-Fougeres to AQUA2015 the international symposium in Aquaculture, August 23-26, 2015, Montpellier, France Monitoring the misuse of certain banned substances in aquacultured products in the European Union, Verdon E. Contribution of Anses-Fougeres to the 3rd SASKVAL Worskshop, June 16-19, 2015, Calgary, Canada New Approaches for the (Broad) Screening of Veterinary Drugs by Full Scan Accurate Mass Determination, Verdon E., Pessel D., Couedor P., Bessiral M., Jagadeshwar-Reddy T., Baletaud S.   Contribution of Anses-Fougeres to the 8th Eurachem Workshop, October 2-5, 2014, Berlin, Germany Difficulties to evaluate the participant's proficiency : the case of the PT for the confirmation of carbadox residues in pig muscle, Fuselier R., Laurentie M., Verdon E. Contribution of Anses-Fougeres to the 3rd edition of the International Symposium on Bee Products, September 28-30, 2014, Opatija, Croatia Evaluation and Validation of a Biochip Multi-Array technology for the simultaneous detection of aminoglycosides, macrolides, lincosamides and other antibiotic residues in honey according to the European guideline for the validation of screening methods, Gaudin V., Hedou C., Soumet C., Verdon E. Contribution of Anses-Fougeres to the 128th Annual Meeting of AOAC International, September 7-10, 2014, Boca Raton, Florida, USA AOAC Collaborative Study for the Analysis of Triphenylmethane Dyes in Seafood, Study...

Oral communications

Published on 09/12/2015

Last updated 2018.05.07   2017 Scientifc session dedicated to developing and validating multi-residue / multi-class screening methods for analysis of chemial contaminants in food usng GC- and LC-chromatography and high resolution mass spectrometry, Co-chaired by Verdon E. (Anses-Fougeres) & Wang J. (CFIA-Calgary) at AOAC International Annual Meeting & Exposition, 18-22 September, 2017, Atlanta, Georgia, USA              1. Sherri TURNIPSEED, US-FDA, ADRC-Denver, "Application of a screening method for drug resdiues in aquacultured products using high resolution mass spectrometry"              2. Dominique HURTAUD-PESSEL, EU-RL Antibiotic VMPR and Dye Residues, Anses-Fougeres, Application of Q-Exactive High Resolution Mass Spectrometry for the Screening of Veterinary Drug Residues"              3. Jon WONG, US-FDA, College Park, "Development, Implementation, ad Use of Mass Spectral Libraries and Compound Databases for Screening Chemical Residues and Contaminants in Foods Using LC-HRMS"   Approaches dealing with the (Broad) Screening of Veterinary Medicinal Product Residues by Full Scan Accurate Mass Determination, VERDON E., Oral Communication at 54th Workshop of NACRW, 23-26 July 2017, Naples, Florida, USA Dye Residue in Aquaculture products: targeted and metabolomics mass spectrometric approahes to track their abuse, DUBREIL E., Oral communication at 54th Workshop of NACRW, 23-26 July 2017, Naples, Florida, USA   2016 Scientific session dedicated to Method Validation and Method Performance Criteria of Chemical Analysis, Co-chaired by Verdon E. (Anses-Fougeres) & Wang J. (CFIA-Calgary) at AOAC International Annual Meeting & Exposition, September 17-21, 2016, Dallas, Texas, USA               1. Jon Wong, US-FDA, College Park, "Validation of Multiresidue Pesticide & Veterinary Drug Methods at FDA"               2. Amadeo Fernandez-Alba, EU-RL Pesticides, Univ Almeria, "EU Quality Control Guidelines for Pesticide Residue Analysis"               3. Louis Bluhm, US-DA, "Progress on CCPR Guidelines for Method Performance Criteria for Pesticides"               4. Paul Zomer, EU-RL GPA, Rikilt-WUR, "High Resolution Mass Spectrometry in View of CD 2002/657/EC and the Future Challenges" Dépistage des résidus de médicaments vétérinaires dans les denrées alimentaires par spectrométrie de masse : LC-MS/MS ou LC-HRMS ?, HURTAUD-PESSEL D., oral communication at Journées Scientifiques de l'AECLDPA, 24 November 2016, La Roche sur Yon, France  Analyse non-ciblée LC-HRMS pour la recherche de biomarqueurs d'exposition: principe et applications, GAUGAIN M., oral communication at the "Séminaire de l'Anses pour les Nouvelles Technologies en Chimie Analytique,  1 June 2016, Maisons-alfort, France Scientifc session dedicated to "New Technologies for Analysis of Chemicals by Mass Spectrometry" co-chaired by VERDON E. & CASELLAS C. at the "Séminaire de l'Anses pour les Nouvelles Technologies en Chimie Analytique", 1 June 2016, Maisons-alfort, France               1. Kaufmann A., KLZH-Switzerland, "Advantages nad drawbacks of new HRMS and LRMS technologies in LC-MS"               2. Junot C., DEA-France, "Apport des nouvelles technologies pour la métabolomique"               3. Hurtaud-Pessel D., Anses-Fougeres, "Dépistage des résidus de médicaments vétérinaires par spectrométrie de masse : LC-MS/MS ou LC-HRMS ?"               4. Biré A., Anses-Maisons-alfort, "Apport du non-ciblé dans l'investigation de TIAC"               5. Martel AC. & Six T., Anses-Sophia antipolis & Anses-DEPR, "Méthodes d'extraction de résidus de pesticides appliquées aux diverses matrices apicoles. Un cadre réglementaire et des LMR en cours de définition" 2015 Tools to Evaluate Pharmacokinetics Data for...

Tasks of the EU-RL :

Published on 18/08/2015

The functions of the EU-RL are the following to promote and develop research on new analytical methods :   to help NRLs of the European Union to implement quality assurance systems to approve validated methods to provide the NRLs with routine methods developed during the MRL procedure to provide the NRLs with information on analytical methods to provide on request the NRLs with opinions on residue assays to organise proficiency testing studies between LNRs to perform analysis in case of disagreement between Member States to organise training sessions for LNRs to provide the Commission with technical and scientific advice to provide the Commission with an annual activity report to help NRLs of Third Countries

The EU-RL Anses-Fougeres Team

Published on 10/07/2015

     

Our EU Partners

Published on 09/07/2015

    The 4 EU-RL Partners from the "Residue Cluster" Anses-Fougeres, France                         The EU-RL mandate website  (direct access) BVL-Berlin, Germany                             The EU-RL Mandate website (direct acces) ISS-CEFAO-Roma, Italy                           The EU-RL mandate website (direct access) Rikilt-Wageningen, Netherlands         The EU-RL mandate website (direct access)     Some other EU partners EC-DG-SANTE Brussels EC-FVO Dublin   EMA London EFSA Parma  

EU-RL Visits

Published on 09/07/2015

  Country Date of Visit Report of the visit Date of report DENMARK 2/6 March 2015 Report of the visit to the Danish NRLs for Residue Control in Food 28 May 2015 CROATIA 15-16 October 2014 Report of the visit to the Croatian NRL for Residue Control in Food 21 January 2015 BELGIUM 16-19 December 2013 Report of the visit to the Belgian NRLs for Residue Control in Food 30 may 2014 SWEDEN 14-15 November 2013 Report of the visit to the Swedish NRL for Residue Control in Food 2 September 2014 MALTA 17-18 December 2012 Report of the visit to the Maltese NRL for Residue Control in Food 17 May 2013 POLAND 29-30 November 2012 Report of the visit to the Polish NRL for Residue Control in Food 14 January 2013 BULGARIA 10-11 October 2011 Report of the visit to the Bulgarian NRL for Residue Control in Food 23 December 2011 HUNGARY 13-14 October 2011 Report of the visit to the Hungarian NRL for Residue Control in Food 23 January 2012 PORTUGAL 18-22 October 2010 Report of the visit to the Portuguese NRLs for Residue Control in Food 17 February 2011 ROMANIA 11-13 November 2009 Report of the visit to the Romanian NRL for Residue Control in Food 25 January 2010 UK 15-16 October 2009 Report of the visit to the British NRL for Residue Control in Food 22 December 2009 ESTONIA 11-12 December 2008 Report of the visit to the Estonian NRL for Residue Control in Food 5 February 2009 FINLAND 08-09 December 2008 Report of the visit to the Finnish NRL for Residue Control in Food 2 March 2009 SLOVAKIA 20-21 November 2008 Report of the visit to the Slovakian NRL for Residue Control in Food 20 January 2009 SLOVENIA 17-18 November 2008 Report of the visit to the Slovenian NRL for Residue Control in Food 19 January 2009 LITHUANIA 10-11 July 2008 Report of the visit to the Lithuanian NRL for Residue Control in Food 29 September 2008 LATVIA 07-08 July 2008 Report of the visit to the Danish NRL for Residue Control in Food 9 September 2008 CZECH REP 12-14 November 2007 Report of the visit to the 2 Czech NRLs for Residue Control in Food 5 March 2008 HUNGARY 25-26 April 2005 Report of the visit to the Hungarian NRL for Residue Control in Food 9 January 2006     Overview of visits to NRLs from 1994 to 2004 25 February 2005 ITALY 30-31 January 2003 Report of the visit to the Italian NRL for Residue Control in Food 4 June 2003 AUSTRIA 11-14 June 2002 Report of the visit to the Austrian NRLs for Residue Control in Food NRL1-LUVIE + NRL2-VMMOE + version in French 26 August 2002 GREECE 28-31 May 2002 Report of the visit to the Greek NRLs for Residue Control in Food  30 June 2002 SPAIN 23-24 May 2002 Report of the visit to the Spanish NRL for Residue Control in Food 30 June 2002 PORTUGAL 19 November 1999 Report of the visit to the Portuguese NRL for Residue Control in Food 19 December 1999  

Our EU Partners

Published on 08/07/2015

                                                                      The 4 EU-RL Partners from the "Residue Cluster"         .  Anses-Fougeres, France :            .  BVL-Berlin, Germany :           .  ISS-CEFAO-Roma, Italy :           .  Rikilt-Wageningen, Netherlands  :      EC-DG-SANTE Brussels Website Link :    EC-FVO Dublin Website Link :   EMA London Website Link :    EFSA Parma Website Link :